WHAT IS CORONA VIRUS , SARS COV2 & COVID-19






corona ye ek latin word hain jiska matlab crown hota hain 
 is virus ki subfamily Ortho-corona-viri-nae hain aur family Corona-viri-dae hain 

ye ek group hain jo RNA viruses se related hote hain mammals aur parindo main kisi bhi tarh ki bimari paida karte hain jabke humans main iski wajah se respiratory tract infections hote hain 


coronavirus ye naam June Almeida and David Tyrrell ne diya jo ke virologist hain sab se phele is naam ko 1968  main ek print main use kiya gaya 
Human corona virus 1960 main discover hua 
1971 main ICTV ( International Committee on Taxonomy of Viruses ) ne is naam ko officially accept kiya 
iski kuch nayi species samne aane par 2009 mai ise 4 categories main devide kiya jo hain -

  • Alphacoronavirus
  • Betacoronavirus
  • Deltacoronavirus
  • Gammacoronavirus

phir 2020 main total 45 species ko recognize / accept kia gya 
in species par continue study ke sath sath kuch aur corona viruses bhi identidy kiye gaye jin main hain
 
  • SARS-CoV - 2003
  • HCoV NL63 - 2003
  • HCoV HKU1 - 2004
  • MERS-CoV - 2013
  • SARS-CoV-2 - 2019

corona virus ka diameter 80 se 120 nanometer tak hota hain kuch Extreme sizes  50 se 200 nm tak bhi hoti hain  
iska total molecular mass lagbhag 40,000 kDa tak hota hain

ye virus jab host cell ke bahar hota hain to lipid bilayer envelope, membrane proteins, aur nucleocapsid ise protect karte hain  

ye virus ek host se dusre host main transmit hota hain depending on the species ye fomite ya fecal-oral route ke zariye hota hain 

human corona viruses ki asal jad bats ko bataya jata hain jabke betacoronaviruses jaise SARS COV 2 ki origin rodents aur bats 
 
corona virus ki wajh se cold, fever, aur sore throat hota hain 
  pneumonia (viral/bacterial ) aur bronchitis jaise bimari bhi ho sakti hain  
is ki wajh se upper aur lower respiratory tract infections bhi hote hai  
 
jo bimari  SARS-CoV se hui ho use SARS kehte hain Severe acute respiratory syndrome coronavirus
jo bimari MERS-CoV se hui ho use  MERS khete hain Middle East respiratory syndrome-related coronavirus
aur jo bimari  SARS-CoV2 se hui ho use COVID-19  kehte hain Severe acute respiratory syndrome coronavirus 2

SARS COV 2 (Severe acute respiratory syndrome coronavirus 2)
 
Is virus ko 2019 novel coronavirus (2019-nCoV) aur  human coronavirus 2019 (HCoV-19 or hCoV-19) bhi kehte hain ye china ke wuhan nami shaher nain discover hua 
SARS COV 2 ek aysa virus hain jis ji wajh se COVID-19 nami bimari hoti hain ise corona virus bhi keh sakte hain par ye sirf virus ka naam nhi balke ek group ka naam hai jis main kafi sare alag alag viruses hote hain SARS COV 2 ye ek betacoronavirus hain jiska origin bats aur rodents hain
 
ye virus contagious hota hain jo bimari ko kafi teezi se phelalta hain 
sars cov 2 ek insan se dusre insan main respiratory droplets (1.8 metres /(6 ft)ke zariye phleta hain jo aam tor par khansne ya cheekne  (coughs or sneezes) se hote hain 
 
ye virus stainless steel par 3 din cardboard par 1 din  copper par 4 ghante  aur plastic par 3 dino tak reh sakta hain jabke soap iske lipid bilayer ko kuch had tak kamzor kar ke virus ko inactivte kar sakti hain  

Har coronavirus ki tarah SARS-CoV-2 main bhi 4 tarh ke strctural protiens hote hain jin main S (spike), E (envelope) aur  M (membrane),hote hain jo ke  viral envelope banate hain jabke 4tha  N (nucleocapsid)  hain  
jismain RNA genome hota hain 
ye virus angiotensin converting enzyme 2 (ACE2) ke zariye human cells main enter karta hain   
angiotensin converting enzyme 2 (ACE2) lungs, arteries, heart, kidney aur  intestines main cell membraines par attach hote hain
 
SARS‑CoV ek positive-sense single-stranded RNA virus hain matlb 
inmain jo genomes hote wo ribonucleic acid se bane hote hain
 positive-sense genome as a messenger RNA (mRNA) kam karte hain



COVID-19


ye ek global pandemic hain jo severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nami virus ki wajh se Hoti hain 
iska full form hain corona virus disease 2019 
q ke ye bimari 2019 main sab se phle China ke shahaer Wuhan main payigyi uske bad dusri jagaho par pheli 
 11 February 2020 ko World Health Organization (WHO) ne is bimari ko  "COVID-19"ka naam diya 


COVID-19 ke symptoms mild se severe hote hain jin main aam tor par sar dard (headache), bukhar (Fever)  khansi (Cough) thakaan (fatigue) hote hain 
iske ilawa 
loss of taste,
loss of smell,
Muscle or joint pain,
Different types of skin rash
Nausea or vomiting,
Diarrhea,aur
sore throat wagira bhi dekhne ko milte hain 
 in symptoms ke ilawa bhi kuch severe symptoms jaise shortness of breath aur pneumonia ho sakte hain 
ye symptoms change ho skate hain depending upon severity of disease or infection 
 
infected logon main kam se kam 5 se 6 dino main COVID 19 ke symptoms show hote hain aur zayda se zyda 14 dino main 

ye bimari tab phleti hain jab koi infected insan kisi dusro se boht nazdeek ho kar khanse, cheenke,  baat kare ya saans le  
yani respiratory route ke zariye ye bimari phelti hain 
covid 19 ek respiratory tract infection hota hain 
 upper respiratory tract main sinuses, nose, aur throat infect hote hain  
jabke lower respiratory tract main windpipe aur lungs 

ye bimari adults main itni severe nahi hoti jitni ki older persons main yani jiki age zyada ho is unhain zyada risk hota hain aur ayse log jinka immune system kamzor ho unhain bhi severe infection ho sakta hain 
kuch bimariya / diseases bhi is risk factor ko badha deti hain jin main hain 

Heart diseases jaise heart failure aur coronary artery disease
Chronic kidney disease
Chronic obstructive pulmonary disease (COPD)
Sickle cell disease
Type 2 diabetes
Obesity
iske ilawa bhi kafi sari conditions hain jo covid 19 patients ke liye serious illness paida kar sakti hain 
  
covid 19 ki wajh se severe medical complications ho sakti is bimari ki wajh se hain kuch logo ki death bhi ho sakti hain 
zyadatar log is bimari se jald hi recover hojate hai par kuch logo main ye serious infection paida karti hain is ke ilawa Covid 19 se jo complications hote hain un main hain 
trouble breathing (saans lene main takleef ) 
Pneumonia 
Blood clots
Organ failure
 acute myocardial injury 
acute kidney injury 
severe lung condition
aur Additional viral and bacterial infections

dekha gaya hain ke kuch baccho main infection hone ke kuch hafto bad severe inflammatory syndrome develop hone ke chances hote hain 

-
covid19 ko detect karne ke liye Rapid diagnostic test (RDT) jaise Antigen test aur Antibody test wagira kiye jate hain  
iske ilawa swab test serology test ya blood test aur Molecular test  ( RNA / PCR) wagira bhi kiye jate hain 
 Chest CT scan bhi COVID-19 ko diagnose karne main kafi helpful hain 

kuch medicine jaise remdesivir, tocilizumab aur dexomethasone covid19 ke treatmnet main diye jate hain 
COVID 19 ko rokne liye RNA vaccines, Inactivated virus vaccines, Adenovirus vector vaccines aur Protein subunit vacciness use ki jati hain 
 jaise Covaxin,covishield,Sputnik V wagira 

is bimari se bachne ke liye aapko kya karna hoga?
 infected logo se doori banye rakhni hogi 
apne hatho ko achi tarh se dhona 
sanitizer ya soap water ka use karna 
apne hatho ko apne chehre se door rakhna yani ankh nak mu par na lagana

COVID 19 kafi tezi se phlene wali bimariyo main se ek hain is bimari se bachne liye zaruri precaution aur vaccines dono lena zaruri hain 










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